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Virus                               
Typical Symptoms                                        
Prevalence                                   
Control/Eradication Potential                                                           
 
 
 
 
**Epstein-Barr Virus (EBV, HHV-4)** 
Usually none in childhood; mild flu-like in some adults 
~90–95% adults worldwide                     
**Eradication unlikely**; latent in B cells for life; vaccines under research           
**Cytomegalovirus (CMV, HHV-5)**    
Mostly asymptomatic; mild fever in some                 
–80% adults globally                       
**Eradication unlikely**; antivirals control infection in high-risk groups              
**Human Herpesvirus-6 (HHV-6A/B)**  
Often asymptomatic; can cause roseola in infants        
Nearly all children infected by age 2        
**Eradication impossible**; lifelong latency in white blood cells                       
**Human Herpesvirus-7 (HHV-7)**     
Usually asymptomatic; mild exanthem in children         
Very high; nearly universal by adulthood     
**Eradication impossible**; latent in lymphocytes                                       
**Herpes Simplex Virus-1 (HSV-1)**  
Usually asymptomatic; cold sores in some                
~70–90% globally                             
**Eradication impossible**; latent in neurons; antivirals suppress outbreaks            
**Herpes Simplex Virus-2 (HSV-2)**  
Often asymptomatic; genital lesions in some             
~11–20% globally (varies by region)          
**Eradication impossible**; latent in neurons; antivirals suppress outbreaks            
**Human Papillomavirus (HPV)**      
Usually asymptomatic; some types cause warts or cancers 
Very high; almost all sexually active adults 
**Partial control possible** via vaccines; eradication unlikely                         
**Adenoviruses**                    
Often mild or asymptomatic; respiratory/GI infections   
Very common; many serotypes                  
**Partial control possible** for some types (military vaccines); eradication impossible 
**Rhinoviruses**                    
Often mild cold or asymptomatic                         
Extremely common; hundreds of serotypes      
**Eradication impossible**; reinfections frequent                                       
**Torque Teno Virus (TTV)**         
Usually asymptomatic                                    
>90% adults                                  
**No intervention needed**; low pathogenicity                                           
**BK Polyomavirus**                 
Usually none                                            
Most adults seropositive                     
**Eradication not feasible**; latent in kidneys; risk in immunocompromised              
**JC Polyomavirus**                 
Usually none                                            
–90% seropositive                          
**Eradication unlikely**; latent in kidneys/brain; disease in immunocompromised         
**Parvovirus B19**                  
Often asymptomatic; mild rash or none                   
Widespread; most adults seropositive         
**Control not practical**; vaccines in development                                      
**Measles virus**                   
Subclinical in rare cases (mostly symptomatic)          
High in unvaccinated populations             
**Eradication possible** with vaccination (symptomatic cases dominate)                  
**Influenza viruses**               
Often mild or asymptomatic (~20–50% of infections)      
Seasonal; global                             
**Control via vaccines**; eradication impossible due to animal reservoirs               
**Noroviruses**                     
Often asymptomatic (~30% infections)                    
Worldwide; common in children and adults     
**Control challenging**; sanitation important; eradication unlikely                     
**Hepatitis B virus (HBV)**         
Often asymptomatic in acute infection                   
~296 million chronic carriers                
**Partial control possible** via vaccination; eradication extremely difficult           
**Hepatitis C virus (HCV)**         
Often asymptomatic (~70–80% infections)                 
~58 million globally                         
**Control possible** via antivirals; eradication difficult due to asymptomatic carriers 
**Poliovirus**                      
Mostly asymptomatic (~72%)                              
Previously widespread                        
**Eradication nearly achieved** with vaccines                                           
**Enteroviruses (non-polio)**       
Usually asymptomatic; mild febrile illness              
Very common                                  
**Eradication impossible**; many serotypes                                              
**Human Coronavirus (seasonal)**    
Often mild or asymptomatic                              
Very common                                  
**Eradication impossible**; vaccines mainly for severe strains                          
**SARS-CoV-2 (COVID-19)**           
Many infections asymptomatic (~20–40%)                  
Pandemic-level prevalence                    
**Control possible via vaccination/masks**; eradication extremely unlikely              
**West Nile Virus**                 
~80% infections asymptomatic                            
Widespread in endemic areas                  
**Control challenging**; eradication impossible                                         
**Zika Virus**                      
Often asymptomatic (~80%)                               
Endemic in tropical areas                    
**Control via vector management**; eradication unlikely                                 
**Dengue Virus**                    
Often mild or asymptomatic (~50%)                       
Endemic in tropics                           
**Control via vector management and vaccines**; eradication difficult                   

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