| Epstein-Barr Virus (EBV, HHV-4) |
Usually none in childhood; mild flu-like in adults |
~90–95% adults worldwide |
Eradication unlikely; latent in B cells; vaccines under research |
| Cytomegalovirus (CMV, HHV-5) |
Mostly asymptomatic; mild fever in some |
50–80% adults globally |
Eradication unlikely; antivirals control infection in high-risk groups |
| Human Herpesvirus-6 (HHV-6A/B) |
Often asymptomatic; can cause roseola in infants |
Nearly all children infected by age 2 |
Eradication impossible; lifelong latency in white blood cells |
| Human Herpesvirus-7 (HHV-7) |
Usually asymptomatic; mild exanthem in children |
Very high; nearly universal by adulthood |
Eradication impossible; latent in lymphocytes |
| Herpes Simplex Virus-1 (HSV-1) |
Usually asymptomatic; cold sores in some |
~70–90% globally |
Eradication impossible; latent in neurons; antivirals suppress outbreaks |
| Herpes Simplex Virus-2 (HSV-2) |
Often asymptomatic; genital lesions in some |
~11–20% globally |
Eradication impossible; latent in neurons; antivirals suppress outbreaks |
| Human Papillomavirus (HPV) |
Usually asymptomatic; some types cause warts or cancers |
Very high; almost all sexually active adults |
Partial control via vaccines; eradication unlikely |
| Adenoviruses |
Often mild or asymptomatic; respiratory/GI infections |
Very common; many serotypes |
Partial control for some types; eradication impossible |
| Rhinoviruses |
Often mild cold or asymptomatic |
Extremely common; hundreds of serotypes |
Eradication impossible; reinfections frequent |
| Torque Teno Virus (TTV) |
Usually asymptomatic |
>90% adults |
No intervention needed; low pathogenicity |
| BK Polyomavirus |
Usually none |
Most adults seropositive |
Eradication not feasible; latent in kidneys; risk in immunocompromised |
| JC Polyomavirus |
Usually none |
70–90% seropositive |
Eradication unlikely; latent in kidneys/brain; disease in immunocompromised |
| Parvovirus B19 |
Often asymptomatic; mild rash or none |
Widespread; most adults seropositive |
Control not practical; vaccines in development |