Viruses That Commonly Infect Humans Asymptomatically

Virus Typical Symptoms Prevalence Control / Eradication Potential
Epstein-Barr Virus (EBV, HHV-4) Usually none in childhood; mild flu-like in adults ~90–95% adults worldwide Eradication unlikely; latent in B cells; vaccines under research
Cytomegalovirus (CMV, HHV-5) Mostly asymptomatic; mild fever in some 50–80% adults globally Eradication unlikely; antivirals control infection in high-risk groups
Human Herpesvirus-6 (HHV-6A/B) Often asymptomatic; can cause roseola in infants Nearly all children infected by age 2 Eradication impossible; lifelong latency in white blood cells
Human Herpesvirus-7 (HHV-7) Usually asymptomatic; mild exanthem in children Very high; nearly universal by adulthood Eradication impossible; latent in lymphocytes
Herpes Simplex Virus-1 (HSV-1) Usually asymptomatic; cold sores in some ~70–90% globally Eradication impossible; latent in neurons; antivirals suppress outbreaks
Herpes Simplex Virus-2 (HSV-2) Often asymptomatic; genital lesions in some ~11–20% globally Eradication impossible; latent in neurons; antivirals suppress outbreaks
Human Papillomavirus (HPV) Usually asymptomatic; some types cause warts or cancers Very high; almost all sexually active adults Partial control via vaccines; eradication unlikely
Adenoviruses Often mild or asymptomatic; respiratory/GI infections Very common; many serotypes Partial control for some types; eradication impossible
Rhinoviruses Often mild cold or asymptomatic Extremely common; hundreds of serotypes Eradication impossible; reinfections frequent
Torque Teno Virus (TTV) Usually asymptomatic >90% adults No intervention needed; low pathogenicity
BK Polyomavirus Usually none Most adults seropositive Eradication not feasible; latent in kidneys; risk in immunocompromised
JC Polyomavirus Usually none 70–90% seropositive Eradication unlikely; latent in kidneys/brain; disease in immunocompromised
Parvovirus B19 Often asymptomatic; mild rash or none Widespread; most adults seropositive Control not practical; vaccines in development

  

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